Genetic testing for BRCA1 and BRCA2 mutations

BRCAaccuTest™ and BRCAaccuTest™ PLUS are a reagent kit for producing libraries for analyzing the BRCA1 and BRCA2 genes using the next generation sequencing (NGS) method, which analyzes genomic DNA derived from blood or FFPE tissue.

For breast and ovarian cancer patients

For HBOC (Hereditary breast and ovarian cancer syndrome) patients

For family history or the age of breast cancer incidence

Working Process

Specification

BRCAaccuTest™ BRCAaccuTest™ PLUS
Certification CE-IVD, MFDS Class III CE-IVD
Target disease Breast/ovarian cancer,
HBOC (Hereditary breast and ovarian cancer syndrome)
Target Enrichment method Amplicon based method
Quantity 24 test
(1 test for control DNA)
12 (6+6) test
(1 test each for control DNA)
Specimen Blood Blood, FFPE tissue, Tissue biopsy
In-put DNA quantity 10-50 ng 10-30 ng
Target gene BRCA1 / BRCA2
Target region 19.8 kb (all protein coding region + intron boundary 10 bp)
amplicon 131 (2 pools) 146 (2 pools)
Hands on time 4.5 hrs 5 hrs
Variants type SNV, INDEL, Dup SNV, INDEL, Dup, CNV*
NGS platform & reagent kit illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano kit, v2, 300cycles
Samples throughput Germline 23 samples Germline 11 samples
Somatic 5 samples
Analysis solution NGeneAnalySys™ v1.1 (CE, MFDS) NGeneAnalySys™ (CE)
*RUO, Research Use Only

Ordering information

Products Cat.no Quantity
RUO CE-IVD
BRCAaccuTest™
& NGeneAnalySys

NGB111R-024

NGB111V-024

24 tests

BRCAaccuTest™ PLUS
& NGeneAnalySys

NGB112R-012

NGB112V-012

12 tests